Tuesday, May 26, 2020

Management of II and Its Impact on the Goals of Organization Free Essay Example, 3250 words

A succeeding, corresponding question that seems to get only occasional or sometimes inadvertent attention is the opportunity problem. This is apprehensive with what opportunities for doing business in a diverse way are opened by IT. Based on field research, approved a more processual viewpoint frequently drawing on studies on improvement. Perhaps several of the business re-engineering literature has given to this domain; for instance Hammer and Champy ( 1993) talk of the require for 'inductive thinking' or the capability first to make out a significant solution and then to ask for the tribulations it that an IT application might solve (Wendy Currie, Bob Galliers, 1999). As most of the business is an information business, perhaps it is obstructive to consider a business strategy and an IT strategy. Perhaps they should be one: an integrated information business strategy. Here business strategy becomes a statement of intent about the future, much as advanced by Hamel and Prahalad ( 19 94) and Hamel ( 1996). More than this, however, the business threats and prospects posed by IT and information resources more extensively are addressed and worked out in the strategy-making process. We will write a custom essay sample on Management of II and Its Impact on the Goals of Organization or any topic specifically for you Only $17.96 $11.86/page The similar significant motive is because few executives have conviction in the analysis of, or plans for, the future which is not stranded in the present.

Friday, May 15, 2020

Relationship Between T Cell Regulation And Type I Diabetes

Abstract The purpose of this study is to explore the relationships and mechanisms between T-cell regulation and type I diabetes by using NOD mice model. NOD mice can spontaneously develop a form of autoimmune diabetes which is similar to human Insulin-Dependent Diabetes Mellitus. T cells can destroy beta cells of the pancreatic islets which can produce insulin. Thus, by analyzing the development of NOD mice autoimmune diabetes to determine potential treatment for type I diabetes. Introduction Diabetes mellitus is a group of metabolic diseases. There are different kinds of diabetes mellitus, but an abnormal blood sugar level over an extended time always can be detected from patients who have this disease. Type one diabetes mellitus also known as insulin-dependent diabetes, patients with this type of diabetes have pancreatic beta cells destruction causing absolute lack of insulin with a tendency to ketoacidosis. It can occur at any age, but more commonly occurs in young people. Patients with acute onset of metabolic disorders symptoms need insulin injections to survive. This type of diabetes including immune-mediated and idiopathic two subtypes. Immune-mediated diabetes often has one or more autoantibodies present, for example, islet cell antibodies (ICA), insulin autoantibodies (IAA) and glutamic acid decarboxylase 65 (GAD65) antibodies. Previous studies have shown that killer T cells that protects us from bacterial damage plays a major role in theShow MoreRelatedCase Control Study961 Words   |  4 Pagesrs3745453 polymorphism on MS risk in a sample of Isfahan population. We found that miR-23a rs3745453 CT variant seem to increase the risk of MS in this population (OR =2.5). Compared with ridolfi et al. The results did not support an association between rs3745453 allele C polymorphism and MS risk(p-value 0.16). Ridolfi et al. in 2013 reported that levels of miR-15b and miR-23a were decreased in the serum of Multiple Sclerosis patients compared with controls. (15). They reported that in MS patientsRead MoreApplication Of Type 1 Diabetes Mellitus3781 Words   |  16 PagesTable of Contents I. Introduction to Type 1 Diabetes Mellitus a. What it is b. Prevalence and demographics c. Treatment II. Cognitive Outcomes: Mood and Memory a. Memory i. Neural Basis of Memory ii. Cognitive Outcome of TIDM on Memory III. Structural Brain Changes: MRI Studies a. The Hippocampus i. Purpose and Function of the Hippocampus ii. Previous studies on T1DM and Hippocampal Volume iii. The Cognitive Effects of T1DM on Hippocampal Volume b. Other Brain Areas IV. Conclusion aRead MoreThe Human Immune System And Its Effects On Disease Development3066 Words   |  13 PagesThe human immune system has advanced to distinguish between and eliminate disease-causing microorganisms. Nevertheless, a symbiotic relationship has been developed with several species of bacteria that not only inhabit the gut, but also make up the natural commensal flora or microbiota. The microbiota, being essential in the breakdown of nutrients, helps prevent colonization by potentially pathogenic bacteria. Also, the gut commensal bacteria appear to be vital in the growth of an efficiently functioningRead MoreEffect Of Ginger On The Brain Of Diabetes Induced Diabetic Rats Essay7558 Words   |  31 Pagesand Embryology, Faculty of Medicine, Menoufia, Egypt a r t i c l e i n f o Article history: Received 3 August 2013 Received in revised form 17 January 2014 Accepted 31 January 2014 Keywords: Ginger Diabetes Brain Histology Immunohistochemistry s u m m a r y Diabetes mellitus results in neuronal damage caused by increased intracellular glucose leading to oxidative stress. Recent evidence revealed the potential of ginger for reducing diabetes-induced oxidative stress markers. The aim of this study isRead MoreEssay on Ambient Air Pollution and Diabetes Mellitus2776 Words   |  12 Pages I. Introduction and Purpose Diabetes mellitus, or simply diabetes, is a disorder in which the body is incapable of fully utilizing converted energy taken from food. There are three types of diabetes: type 1 or insulin-dependent, type 2 or adult on-set, and gestational diabetes (Webmd.com, 2014). According to the American Diabetes Association, in 2011 there were approximately 25.8 million cases of diabetes in the United States, 7 million of which were undiagnosed, and an estimated 79 millionRead MoreDementia And It s Types Essay1429 Words   |  6 PagesDementia and it s types Dementia is a syndrome caused by multiple progressive illnesses that affects memory, thinking, orientation, behaviour, comprehension, calculation, judgement, learning capacity, language, and loss of motivation and emotional control. The syndrome is characterized by Alzheimer’s disease, dementia with lewy bodies, vascular dementia, and frontotemporal dementia. Dementia mainly affects older people. Alzheimer disease is the most common form of dementia. Prevalence 44.4Read MoreEvidence Suggesting Three Plausible Functions Of Sleep1312 Words   |  6 Pageskey aspects are explained in detail with regards to studies. The findings from the studies will help justify the function and it’s involvement with sleep. Sleep is important for an individual’s well being, survival, brain development, emotional regulation, cognitive function, memory, and in order to protect mental and cardiovascular health. An individual should sleep for 6-8 hours. A recent suggestion by the American Academy of Sleep Medicine recommended that an individual should sleep for minimumRead MoreCurrent Mechanism And Concepts Of Pathogenesis Of Atherosclerosis1890 Words   |  8 Pagestheir ensuing management. The progression of atheroma consist of several cellular and molecular events with endothelial dysfunction, leucocyte recruitment and dispedesis, LDL transcytosis, LDL oxidation, recruitment and proliferation of smooth muscle cells, synthesis of extracellular ma trix proteins, build-up of foamy macrophages as well as interplay of different cytokines. (Bisht et al, 2012). Atherosclerosis known as the leading cause of death globally - has established much attention as to its originsRead MoreEssay on Role of Inflammation in Atherosclerosis8530 Words   |  35 PagesStudies on the pathophysiology of this disease has evolved over the past three decades, and a fusion of these views has led to the concept of the atheroma as a graveyard of acellular lipid debris enrobed by a capsule of proliferated smooth muscle cells. Atherosclerosis, formerly considered as a bland lipid storage disease, actually involves an ongoing inflammatory response that results in a host of complications including ischaemia, acute coronary syndromes and stroke. Recent advances in cellularRead MoreThe Effect Of Nonalcoholic Fatty Liver Disease ( Nafld ) Essay1776 Words   |  8 PagesBackground: Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease commonly associated with obesity, type 2 diabetes, and inflammation-all features of insulin resistant syndrome. However, very limited data are available regarding the association of subclinical inflammation and insulin resistance with NAFLD in a prediabetic state. We, therefore, conducted the study to assess this relationship among this population. Methods: We studied a cross-sectional analytical design of 140 [male/female, 77/63;

Wednesday, May 6, 2020

Everyone Has the Capacity to Do Evil Essay - 1189 Words

Throughout time humans have been trying to explain the nature of evil and man’s relationship with evil. Many have come up with an explanation that seems logic but yet some still disagree. In this case the authors of Macbeth, Dr. Jekyll and Mr. Hyde, the Picture of Dorian Gray, Paradise lost, and Beowulf all share the same concept that anyone has the capacity to do evil, but they disagree with each other on the idea that evil is not a choice. All these writers agree that any individual has the capacity to do evil. Sometimes the most reliable of people can end up betraying someone else as seen in the case of King Duncan from the play of Macbeth by William Shakespeare. King Duncan was a good King but his greatest flaw was to always trust the†¦show more content†¦79). Oscar Wilde the author of the Picture of Dorian Gray also shares the same view as the quote from Dr. Jekyll and Mr. Hyde that everybody is two different people the good and the evil. Dorian Gray was a handsome and wealthy young gentleman who became extremely concerned about preserving his beauty and to pursue his own pleasure above all else after he became influenced by the teachings of Lord Henry. â€Å"There were moments when he looked on evil simply as a mode through which he could realize his conception of the beautiful.† (ch.11) his obsession with beauty drives him to commit serious crimes such as the murder of his friend Basil and the contribution to the deaths of other people such as the suicide of his beloved Sibyl Bane whom Dorian left broken hearted. He also contributes indirectly to the death of Sibyl’s brother James after he seeks revenge against Dorian for the death of his sister. He also contributed to the suicide of Adrian Singleton, whom rumors say Doria n corrupted. His crimes where somewhat reflected in the painting that Basil had done for him. â€Å"The quivering, ardent sunlight showed him the lines of cruelty round the mouth as clearly as if he had been looking into a mirror after he had done some dreadful thing.†(pg.107) In Paradise lost by John Milton Gods most high ranked angel Satan wages a war against heaven. â€Å"O sun, to tell thee how I hate thy beams that bring to my remembranceShow MoreRelatedWhy Not Everyone Is A Torturer By Oliver Behrensdorff Essay1192 Words   |  5 Pagesï » ¿Why Not Everyone Is A Torturer - Oliver Behrensdorff What are the causes of atrocity events such as the massacre at My Lai, the abuse and torture of Iraqi prisoners in Abu Ghraib or the extermination of Jews during World War II? Whether groups of people bestowed with unaccountable power naturally resort to violence or not, the subject is indeed controversial. Arguably, the less restrictions that one must follow, the higher the risk becomes of one to condone violence. However, how can we explainRead MoreThe Devil Within William Golding s Lord Of The Flies1152 Words   |  5 Pagesinherently evil. He uses figures representing evil, scientific intelligence, and authority. He ties it all together to create a page turning novel. Golding s use of symbols such as the beast, Piggy’s glasses, and the conch, indicates that humans, when detached from society s rules, allow their natural capacity for evil to dictate their existence. The beast symbolizes evil and darkness. The beast is a tangible source of evil on the island. It represents the evil naturally present within everyone. SimonRead MoreGood vs. Bad of Dr. Jekyll and Mr. Hyde by Robert Louis Stevenson932 Words   |  4 Pagesperson. Certain behaviors were highly restricted for example, showing evil. Instead, they were expected to give respect for everyone. People who acted out against the norm during this period were usually sent to asylums because such behaviors were unacceptable. People in this society did just that, they behaved as if they were perfectly normal. This does not mean that their bad side did not exist. Instead, they hid their evil side from the public, letting all their anger out at home in private. Stevenson’sRead MoreTaking a Look at Utilitarianism655 Words   |  3 PagesIntroduction Living as a utilitarian is more easily expressed than done. Thinking about the betterment of humanity is not something everyone wants to cerebrate or worry about. Ideally, utilitarianism would be prosperous if the view was shared among the world. Coming in from a thoroughly nescient perspective, I was unsure of the possibilities, and unsure of the impact I would have on a topic I knew nothing about. Explanation of Utilitarianism Utilitarianism is the subsistence of pleasure and theRead MoreJohn Hobbes View Of Action And The Will As An Examination Of Human Psychology893 Words   |  4 Pagesimpulse towards something, and aversion, an impulse away from something (Lev, p. 38). Appetite indicates that the thing being considered is â€Å"good,† while aversion indicates that it is â€Å"evil.† Whether something causes an appetite or aversion is context and time dependent, so nothing can be objectively good or evil (Lev, p. 39). In fact, quite often a particular object or action will produce in a human mind a sequence of both appetites and aversions. In these cases, the mind engages in a process ofRead More Rigidity of Puritanism Exposed in Hawthornes Young Goodman Brown1268 Words   |  6 Pagesillustrates this through Browns actions.   When Brown lives a righteous life with good faith, his thoughts remain pure and happy.   He has a wonderful wife, and he enjoys the presence of everyone.   As he takes his walk into the forest and into evil ways, his hopes and faith disappear.   He no longer loves his wife in the same way, and he despises everyone whom people consider were holy.   When he loses his faith, he loses his happiness.   To regain his happiness, Brown must findRead MoreIs Disobeying A Higher Power?1194 Words   |  5 PagesFor as long as history has been recorded the human species has been subject to authority. There has always been somebody for people to answer to. God, a king, or even an elected official. After an extensive history of obeying a higher power the concept has become part of our species culture.Rebellion is frowned upon by society and compliance is expected. When is it right to break the chain and disobey? According to Socrates it is never right to disobey authority, he says â€Å"Consider the logical consequenceRead MoreObedience, By Stanley Milgram853 Words   |  4 Pagespracticed everyday throughout everyone s life. It has been engraved in everyone growing up. Students are taught at an early age to obey the higher authority’s commands in school, at home, and in public whether it is the teacher, principal, police officer, and even other parents. Additionally, parents t oo have to practice obedience. They must be follow orders from their bosses, and they must obey the laws. As a result, obedience becomes second nature, which exposes everyone to problems. The problemsRead MoreCharacters And Symbols In The Scarlet Letter By Nathaniel Hawthorne1077 Words   |  5 Pagespurpose† (95). The Puritans believe she has committed an awful crime. For her punishment she must walk around with an â€Å"A† on her bosom. The â€Å"A† represents adultery. Despite how the people in the town treat her and what they say about her she still sees the A as a symbol for her to represent how she is able to overcome the sin and show that there is good in herself, even though she receives public humiliation and isolation from the Puritans. To show she still has strength in her, she fights to keepRead MoreWhat Makes A Monster? Essay1461 Words   |  6 Pagesreal, ghosts are real too. They live inside us, and sometimes they win†. It had taken me awhile to truly grasp what King had meant, but then it clicked. Everyone has a monster inside them, dormant or not. That monster is the voice we hear in the back of our heads, urging us to cheat or to steal, and in some instances, worse. That monster is the evil that resides in each and every one of us, which is why I believe humans rely so heavily on the fiction aspect behind the monster. Not only does it shelter

Tuesday, May 5, 2020

Classical and Neo Classical Theories free essay sample

Classical and Neo-Classical Theories of Management Classical management theory There are three well-established theories of classical management: Taylor,s Theory of Scientific Management, Fayol’s Administrative Theory, Weber’s Theory of Bureaucracy. Although these schools, or theories, developed historical sequence, later ideas have not replaced earlier ones. Instead, each new school has tended to complement or coexist with previous ones. Theory recognizing the role that management plays in an organization. The importance of the function of management was first recognized by French industrialist Henri Fayol in the early 1900s. In contrast to the purely scientific examination of work and organizations conducted by F W Taylor, Fayol proposed that any industrial undertaking had six functions: technical; commercial; financial; security; accounting; and managerial. Of these, he believed the managerial function, ‘to forecast and plan, to organize, to command, to coordinate, and control’, to be quite distinct from the other five. Fayol also identified general principles of management: division of work; authority and responsibility; discipline; unity of command; unity of direction; subordination of individual interest to general interest; remuneration of personnel; centralization; scalar chain of authority; order; equity; stability of tenure of personnel; initiative; and esprit de corps. Fayols views on management remained popular throughout a large part of the 20th century. Evolution of Classical Approach to Management Traditional process of learning is either through obsevation and experiment. Nature or environment is considered uniform and when we observe certain phenomenon or events uniformly leading to the same result or results, we conclude a cause and effect relationship between the two. This is learning by observation or in other words by experience. Earlier thinkers on management followed this approach in developing theories of management. Learning principally is through emphirical process and through analysis of the data collected through observation. Draw the principles of managment by looking at and anyalysing the jobs that all managers commonly do. This approach served as a starting point for pioneers on management science to verify the validity and improve the applicability of the principles and practices of management. Analysis of observd data is what constitute a case study. The observational method of case study helps arriving at logical conclusions about past experience and to test the same as standards for future events. The German sociolists, Max Weber followed the classical approach and developed his theory of Bureaucracy, which portrays the structure anddesign of organisation charqacterised by a hierarchy of authority, formalised rules and regulations that serve to guide the coordinated functioning of an organization. Basic Postulates of the Classical Approach by Max Weber 1. Management of an organization is considered as a chain of inter-related functions. The study of the scope and features of these functions, the sequence through which these are performed and their inter-relationship leads one to draw principles of management suitable for universal application 2. Learning principles of management is done through the past experiences of actual practicing managers 3. As business environment consists of uniform cycles exhibiting an underlying unity of realities, functions and principles of management derived through process of empirical reasoning are suitable for universal application 4. Emerging new managers through formal education and case study can develop skill and competency in management concepts and practices 5. The clasasical approach also recognised the importance of economic efficiency and formal organizational structure as guiding pillars of management effectigveness. 6. Business activity is based on economic benefit. Organizations should therefore control economic incentives Neoclassical theory of management There are 3 neoclassical theories: Human Relations theory : Explains the modern advancement of Human Relations Management theory which takes into account human factors like the employer-employee relationship. Human relations theory is largely seen to have been born as a result of the Hawthorne experiments which Elton Mayo conducted at the Western Electrical Company. The important strand in the development of modern management was the increase in attention to the human factors, which has become known as the human relations school of management. ’ The core aspect of Human Relations Theory is that, when workers were being observed and included in the research, they felt more important and valued by the company. As a result, their productivity levels went up significantly. This represented a significant departure from many of the classical theories, particularly Fordism, as it went against the notion that management needed to control workers, and remove their autonomy at every step. Instead, it showed that by engaging with workers and considering their requirements and needs, company’s could benefit from increased productivity. Behavioral theory : The behavioral management theory is often called the human relations movement because it addresses the human dimension of work. Behavioral theorists believed that a better understanding of human behavior at work, such as motivation, conflict, expectations, and group dynamics, improved productivity. The theorists who contributed to this school viewed employees as individuals, resources, and assets to be developed and worked with — not as machines, as in the past. Several individuals and experiments contributed to this theory. Social systems theory. : Developed by Niklas Luhmann is an option for the theoretical foundation of Human Resource Management (HRM). After clarifying the advantages of using a grand (social) theory as the basic theoretical perspective, the roots of this social systems theory the deterministic view of systems as machines, the open systems approach and non-linear systems theory are addressed. Based on the view of social systems as autopoietically closed systems, five major contributions to a theoretical foundation of HRM are identified: (1) the conceptualisation of organising and managing human resources as social processes, thus overcoming an individualistic angle; (2) the new importance of individuals as essential element in the systems environment; (3) the abstention form far reaching or highly unrealistic assumptions about the nature of human beings; (4) the interaction between various levels and units of analysis built into the theory which is essential for comprehensive and in-depth analyses of HR phenomena and (5) the openness for additional theories for which social systems theory provides the overall framework. George Elton Mayo was in charge of certain experiments on human behavior arried out at the Hawthorne Works of the Western Electric company in Chicago between 1924 and 1927. His research findings have contributed to organizational development in terms of hu man relations and motivation theory. Elton Mayos contributions came as part of the Hawthorne studies, a series of experiments that rigorously applied classical management theory only to reveal its shortcomings. The Hawthorne experiments consisted of two studies conducted at the Hawthorne Works of the Western Electric Company in Chicago from 1924 to 1932. The first study was conducted by a group of engineers seeking to determine the relationship of lighting levels to worker productivity. Surprisingly enough, they discovered that worker productivity increased as the lighting levels decreased — that is, until the employees were unable to see what they were doing, after which performance naturally declined. A few years later, a second group of experiments began. Harvard researchers Mayo and F. J. Roethlisberger supervised a group of five women in a bank wiring room. They gave the women special privileges, such as the right to leave their workstations without permission, take rest periods, enjoy free lunches, and have variations in pay levels and workdays. This experiment also resulted in significantly increased rates of productivity. In this case, Mayo and Roethlisberger concluded that the increase in productivity resulted from the supervisory arrangement rather than the changes in lighting or other associated worker benefits. Because the experimenters became the primary supervisors of the employees, the intense interest they displayed for the workers was the basis for the increased motivation and resulting productivity. Essentially, the experimenters became a part of the study and influenced its outcome. This is the origin of the term Hawthorne effect, which describes the special attention researchers give to a studys subjects and the impact that attention has on the studys findings.